Monday Night Football is on ESPN again in 2019. ESPN (and ABC) has been the home for “Monday Night Football” since its inception in 1970. Games start at 8:15 p.m. ET unless otherwise noted.
| Week 1 | Sept. 9 | Texans at Saints (7 p.m. ET) |
| Sept. 9 | Broncos at Raiders (10:15 p.m. ET) | |
| Week 2 | Sept. 16 | Browns at Jets |
| Week 3 | Sept. 23 | Bears at Redskins |
| Week 4 | Sept. 30 | Bengals at Steelers |
| Week 5 | Oct. 7 | Browns at 49ers |
| Week 6 | Oct. 14 | Lions at Packers |
| Week 7 | Oct. 21 | Patriots at Jets |
| Week 8 | Oct. 28 | Dolphins at Steelers |
| Week 9 | Nov. 4 | Cowboys at Giants |
| Week 10 | Nov. 11 | Seahawks at 49ers |
| Week 11 | Nov. 18 | Chiefs at Chargers |
| Week 12 | Nov. 25 | Ravens at Rams |
| Week 13 | Dec. 2 | Vikings at Seahawks |
| Week 14 | Dec. 9 | Giants at Eagles |
| Week 15 | Dec. 16 | Colts at Saints |
| Week 16 | Dec. 23 | Packers at Vikings |